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Life extension Life extension consists of attempts to extend human life beyond the natural lifespan. So far none has been proven successful in humans. Several aging mechanisms are known, and anti-aging therapies aim to correct one or more of these: Dr. Leonard Hayflick discovered that mammalian cells divide only a fixed number of times. This "Hayflick limit" was later proven to involved in the synthesis of dTMP (2'-deoxythymidine-5'-phosphate) from dUMP (2'-deoxyuridine-5'-phosphate). The pathway in the formation of tetrahydrofolate (FH4) is the reduction of folate (F) to dihydrofolate (FH2) by folate reductase, and then the subsequent reduction of dihydrofolate to tetrahydrofolate (FH4) by dihydrofolate reductase. Methylene tetrahydrofolate (CH2=FH4) is formed from tetrahydrofolate by the addition of methylene groups from one of three carbon donors: formaldehyde, serine, or glycine. Methyl tetrahydrofolate (CH3-FH4) can be made from methylene tetrahydrofolate by reduction of the methylene, and methylidine tetrahydrofolate (CHO-FH4) is made by oxidation of the methylene tetrahydrofolate. In other words: F → FH2 → FH4 → |
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Will The Real Fitness Hormone Please Stand Up - WILL THE REAL FITNESS HORMONE PLEASE STAND UP! New Medical Research shows high-intensity exercise can increase the body’s natural production of the fitness hormone by 530%! By Phil Campbell, M.S., M.A., FACHE When I completed the research phase for a health and fitness book in 2002, the bio-medical research was complete enough to draw hard conclusions about the type of fitness program that would make your body increase anti-aging, an... |
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