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Hormone replacement therapy Hormone replacement therapy This article is about the treatment with sex steroids. For hormone replacement therapy in general, and for other instances in which hormones might be prescribed, see hormone therapy. Hormone replacement therapy (HRT) is a system of medical treatment for postmenopausal women, based on the assumption that it may Menopause Menopause Menopause (also known as the "Change of life" or climacteric) is a stage of the reproductive lifecycle that every woman goes through at some point in her life, usually in the fifth or sixth decade, where the ovaries stop producing estrogen. (A similar mechanism in men is known as andropause.)

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