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IGF-II is thought to be a primary growth factor required for development while IGF-I expression is seen in later life. Gene knockout studies in mice have confirmed this though other animals are likely to regulate the expression of these genes in distinct ways. While IGF-II may be primarily fetal in action it is also essential for development and function of organs such as the brain, liver and kidney. IGF-I is mainly secreted by the liver as a result of stimulation by Human Growth Hormone (hGH). Almost every cell in the human body is affected by IGF-I, especially cells in muscle, cartilage, value. Every cell is capable of producing a vast number of regulatory molecules - tissue hormones, neurotransmitters, cytokines and many more. The classical endocrine glands and their hormone products are only better specialized to serve regulation on the overall organism level. Nevertheless they can in many instances be used in other ways or only on the tissue level. The most important hormones in humans include: adrenaline - synonymous with epinephrine adrenocorticotropic hormone (ACTH) aldosterone angiotensinogen antidiuretic hormone (ADH) atrial-natriuretic peptide (ANP) calciferol (vitamin D3) calcitonin cholecystokinin (CCK) corticotropin-releasing hormone (CRH) cortisol dopamine erythropoietin (EPO) follicle stimulating hormone (FSH) gastrin glucagon gonadotropin-releasing |
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HGH Human Growth Hormone and Hypothyroidism - The Thyroid Gland and Thyroid Hormone The thyroid gland is a butterfly shaped gland that is located over the trachea (wind pipe) just below the larynx (voice box). The thyroid gland plays a very important role in most all the metabolic processes of the body. The thyroid gland with its thyroid hormone is responsible for regulating metabolism. How Thyroid Hormone is Made The hypothalamus, often referred to as the body`s "thermostat"... |
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